Premier Hotels on Wade Hampton Blvd Greenville SC

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Greenville, a charming city nestled in the center of South Carolina, is renowned for its captivating blend of Southern hospitality and modern allure. As you explore this vibrant destination, the thoroughfare of Wade Hampton Boulevard stands out as a hub of exquisite accommodations. The hotels lining this boulevard offer a diverse array of options, from luxury boutique stays to cozy budget-friendly establishments, ensuring that every traveler finds their perfect retreat.

When seeking a memorable stay in Greenville emerges as a prime choice for accommodation. With its convenient location, visitors are treated to easy access to some of the city's finest attractions, including cultural landmarks, shopping districts, and culinary delights. Whether you yearn for a rejuvenating spa experience, a taste of local flavors, or a peaceful retreat after a day of exploration, the hotels along this bustling boulevard cater to every need with unparalleled hospitality.

Immerse yourself in the quintessential Southern charm of Greenville by choosing one of the hotels on Wade Hampton Boulevard as your home away from home. From personalized service to top-notch amenities, these establishments blend modern comforts with Southern grace for an unforgettable stay. Indulge in the scenic beauty of Greenville and let the hotels on Wade Hampton Boulevard elevate your experience, ensuring that your visit to this enchanting city is nothing short of exceptional.
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Our Top 6

(Sorted by rating & number of reviews)

1. Best Western Plus Suites Greenville
2. Econo Lodge
3. Baymont By Wyndham Greenville
4. Courtyard Greenville
5. Knights Inn Greenville
6. Quality Inn Greenville Near University

Luxury Hotels on Wade Hampton Blvd Greenville SC

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Greenville
Feb 06, 2026 - Feb 07, 2026

Best Western Plus Suites Greenville

8.7

Good

(720 Reviews)

+ 88 photos
Best Western Plus Suites Greenville seamlessly blends modern convenience with timeless elegance along Wade Hampton Boulevard. The hotel's spacious suites are elegantly decorated, providing a relaxing retreat for travelers seeking a luxurious stay in Greenville. With its exceptional service and prime location, this establishment epitomizes upscale hospitality in the center of the city.
Address: 2310 Greenville Boulevard Ne
Rating: Good 8.7 (720 Reviews)
Rooms: 70
Price: From 100$

Econo Lodge

7.0

Good

(321 Reviews)

+ 50 photos
Econo Lodge Greenville offers a budget-friendly option on Wade Hampton Boulevard, providing clean and simple accommodations for travelers on a tight budget. With its convenient location and basic amenities, this hotel is perfect for those seeking a no-frills stay in Greenville. Experience affordability without sacrificing comfort at this value-oriented establishment in the very heart of the city.
Address: 920 Cross Winds Street
Rating: Good 7.0 (321 Reviews)
Rooms: 41
Price: From 61$

Budget-Friendly Hotels on Wade Hampton Blvd Greenville SC

For travelers seeking affordable yet comfortable accommodations along Wade Hampton Boulevard in Greenville, these budget-friendly hotels provide a welcoming stay without compromising on quality. From cozy rooms to convenient amenities, these establishments offer a wallet-friendly option for exploring the city's attractions without breaking the bank.

Baymont By Wyndham Greenville

5.8

Good

(457 Reviews)

+ 48 photos
Baymont By Wyndham Greenville blends affordability with quality service along Wade Hampton Boulevard, making it an excellent choice for budget-conscious travelers. The hotel's cozy rooms and convenient location provide a comfortable base for exploring Greenville's diverse offerings. Enjoy a pleasant stay that won't strain your wallet at this welcoming hotel in the very heart of the city.
Address: 3439 S Memorial Drive
Rating: Good 5.8 (457 Reviews)
Rooms: 103
Price: From 58$

Courtyard Greenville

7.9

Good

(283 Reviews)

+ 45 photos
Courtyard Greenville on Wade Hampton Boulevard caters to business travelers with its well-equipped business center, meeting facilities, and comfortable workspaces. The hotel's modern design and convenient location make it a top choice for professionals visiting Greenville for work. Whether conducting meetings or unwinding after a busy day, business travelers will appreciate the efficiency and professionalism of Courtyard Greenville.
Address: 2225 Stantonsburg Road (Us 264)
Rating: Good 7.9 (283 Reviews)
Rooms: 115
Price: From 123$

Family-Friendly Hotels on Wade Hampton Blvd Greenville SC

Families traveling to Greenville will find a warm welcome at these family-friendly hotels located on Wade Hampton Boulevard. With a focus on comfort and convenience for guests of all ages, these accommodations offer a range of amenities and services to ensure a memorable stay for the whole family. From spacious rooms to on-site activities, these hotels cater to the unique needs of families seeking an unforgettable vacation in Greenville.

Knights Inn Greenville

4.0

Good

(139 Reviews)

+ 16 photos
Knights Inn Greenville on Wade Hampton Boulevard is a family-friendly establishment that prioritizes comfort and affordability for travelers with children. The hotel's family rooms and accommodating staff create a welcoming environment for families looking to enjoy a relaxing stay in Greenville. With easy access to local attractions and a range of family-oriented services, Knights Inn Greenville ensures an enjoyable experience for families visiting the city.
Address: 3435 South Memorial Drive
Rating: Good 4.0 (139 Reviews)
Rooms: 58
Price: From 59$

Quality Inn Greenville Near University

6.9

Good

(611 Reviews)

+ 61 photos
Quality Inn Greenville Near University offers a budget-friendly stay with clean and comfortable rooms, ideal for travelers looking for affordable accommodations in Greenville. This hotel on Wade Hampton Boulevard provides easy access to the city's attractions while offering essential amenities such as complimentary breakfast and free Wi-Fi. Experience comfort and convenience without overspending at this value-for-money establishment.
Address: 821 South Memorial Drive
Rating: Good 6.9 (611 Reviews)
Rooms: 110
Price: From 70$

Business-Friendly Hotels on Wade Hampton Blvd Greenville SC

For business travelers seeking a seamless stay in Greenville, these business-friendly hotels along Wade Hampton Boulevard offer a blend of comfort and convenience tailored to the needs of corporate guests. With thoughtfully designed amenities and services, these accommodations provide a productive environment for business travelers to work, connect, and unwind during their stay in Greenville.